Please use this identifier to cite or link to this item: http://hdl.handle.net/10174/13951

Title: Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies
Authors: Alexandre, Nuno
Ribeiro, Jorge
Gärtner, Andrea
Pereira, Tiago
Amorim, Irina
Fragoso, João
Lopes, Ascensão
Fernandes, João
Costa, Elísio
Santos-Silva, Alice
Rodrigues, Miguel
Santos, José Domingos
Maurício, Ana Colette
Luís, Ana Lúcia
Issue Date: 2014
Citation: Alexandre, Nuno; Ribeiro, Jorge; Gärtner, Andrea; Pereira, Tiago; Amorim, Irina; Fragoso, João; Lopes, Ascensão; Fernandes, João; Costa, Elísio; Santos-Silva, Alice; Rodrigues, Miguel; Santos, José Domingos; Maurício, Ana Colette; Luís, Ana Lúcia. Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies , Journal of Biomedical Materials Research Part A, 102, 12, 4262-4275, 2014.
Abstract: Polyvinyl alcohol hydrogel (PVA) is a synthetic polymer with an increasing application in the biomedical field that can potentially be used for vascular grafting. However, the tissue and blood–material interactions of such gels and membranesare unknown in detail. The objectives of this study were to: (a) assess the biocompatibility and (b) hemocompatibility of PVA-based membranes in order to get some insight into its potential use as a vascular graft. PVA was evaluated isolated or in copolymerization with dextran (DX), a biopolymer with known effects in blood coagulation homeostasis.
URI: http://hdl.handle.net/10174/13951
Other Identifiers: 15493296
Type: article
Appears in Collections:ZOO - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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