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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10174/13951
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Title: | Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies |
Authors: | Alexandre, Nuno Ribeiro, Jorge Gärtner, Andrea Pereira, Tiago Amorim, Irina Fragoso, João Lopes, Ascensão Fernandes, João Costa, Elísio Santos-Silva, Alice Rodrigues, Miguel Santos, José Domingos Maurício, Ana Colette Luís, Ana Lúcia |
Issue Date: | 2014 |
Citation: | Alexandre, Nuno; Ribeiro, Jorge; Gärtner, Andrea; Pereira, Tiago; Amorim, Irina; Fragoso, João; Lopes, Ascensão; Fernandes, João; Costa, Elísio; Santos-Silva, Alice; Rodrigues, Miguel; Santos, José Domingos; Maurício, Ana Colette; Luís, Ana Lúcia. Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting- In vitro and in vivo studies , Journal of Biomedical Materials Research Part A, 102, 12, 4262-4275, 2014. |
Abstract: | Polyvinyl alcohol hydrogel (PVA) is a synthetic polymer with an increasing application in the biomedical field that can potentially be used for vascular grafting. However, the tissue
and blood–material interactions of such gels and membranesare unknown in detail. The objectives of this study were to: (a) assess the biocompatibility and (b) hemocompatibility of PVA-based membranes in order to get some insight into its potential use as a vascular graft. PVA was evaluated isolated or in copolymerization with dextran (DX), a biopolymer with known effects in blood coagulation homeostasis. |
URI: | http://hdl.handle.net/10174/13951 |
Other Identifiers: | 15493296 |
Type: | article |
Appears in Collections: | ZOO - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
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