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Title: Mitochondrial DNA in human identification: a review
Authors: Amorim, António
Fernandes, Teresa
Taveira, Nuno
Keywords: mtDNA
Human identification
Legal medicine
Forensic biology
Issue Date: Aug-2019
Publisher: PeerJ Life and Environment
Citation: AmorimA.,FernandesT.,TaveiraN.. 2019. MitochondrialDNAinhuman identification: areview. PeerJ 7:e7314
Abstract: Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population data bases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of human identification focusing on the most relevant issues for forensics.
Type: article
Appears in Collections:BIO - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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