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Title: Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines
Authors: Marques, Carolina S.
Locati, Abel
Prates Ramalho, J.P.
Burke, Anthony J.
Issue Date: 2015
Citation: Marques, Carolina S.; Locati, Abel; Prates Ramalho, J.P.; Burke, Anthony J.Palladium catalysed sequential imine arylation/Suzuki–Miyaura coupling: synthesis of a-(biarylyl)benzylamines, Tetrahedron, 71, 21, 3314-3324, 2015.
Abstract: report an innovative, high yielding one-pot sequential catalytic imine arylation/SuzukieMiyaura cross-coupling reaction, which converts suitably activated imine substrates to various biarylarylmethyl amine products using several commercial Pd catalysts. Many biarylarylmethyl amine molecules are biologically active. Insightful computational studies detail the mechanism of the imine arylation process. The sequence of reactions is likely to be dependent on the reaction conditions.
Other Identifiers: 00404020
Type: article
Appears in Collections:CQE - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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