Please use this identifier to cite or link to this item: http://hdl.handle.net/10174/5728

Title: Expressão imunoistoquímica da proteína S-100 na discondroplasia da tíbia
Authors: Capela e Silva, F
Lamy E, E
Reis, J
Potes, J
Pereira, A
Cabrita AS, AS
Keywords: Discondroplasia da tibia
S-100
Imuno-histoquímica
Issue Date: 2010
Citation: Capela e Silva F, Lamy E, Reis J, Potes J, Pereira A, Cabrita AS. Expressão imunoistoquímica da proteína S-100 na discondroplasia da tíbia. Arq Bras Med Vet Zootec 2010; 62: 495-498.
Abstract: It was compared, by immunohistochemistry, the expression of S-100 protein from normal and tibial dyschondroplasia (TD) growth plates. The results suggest that S-100 may be involved in growth plate homeostasis. The expression of S-100 in dyschondroplastic chondrocytes may be due to a low level of calcium in the lesion and/or compression of chondrocytes by the accumulated matrix. One further possibility is the association between S-100 and the regulation of matrix metalloproteinases (MMPs) and their endogenous inhibitors (TIMPs). Further studies will be necessary to provide insight into involvement of S-100 in tibial dyschondroplasia development and the precise nature of the pathology.
URI: http://www.scielo.br/pdf/abmvz/v62n2/35.pdf
http://hdl.handle.net/10174/5728
Type: article
Appears in Collections:ICAAM - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
BIO - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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