Please use this identifier to cite or link to this item:
|Title: ||Characterization of glutathione S transferases from the plant-parasitic nematode, Bursaphelenchus xylophilus|
|Authors: ||Espada, Margarida|
|Keywords: ||detoxification metabolism,|
|Issue Date: ||2016|
|Abstract: ||We have previously identified two secreted glutathione S-transferases (GST) expressed in the pharyngeal gland cell of
Bursaphelenchus xylophilus, which are upregulated post infection of the host. This study examines the functional role of GSTs in B.
xylophilus biology. We analysed the expression profiles of all predicted GSTs in the genome and the results showed that they belong to
kappa and cytosolic subfamilies and the majority are upregulated post infection of the host. A small percentage is potentially secreted
and none is downregulated post infection of the host. One secreted protein was confirmed as a functional GST and is within a cluster that
showed the highest expression fold change in infection. This enzyme has a protective activity that may involve host defences, namely
in the presence of terpenoid compounds and peroxide products. These results suggest that GSTs secreted into the host participate in the
detoxification of host-derived defence compounds and enable successful parasitism.|
|Appears in Collections:||BIO - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.