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Title: Differential response to isoproturon by two strains of Saccharomyces cerevisiae.
Authors: Candeias, M
Alves-Pereira, I
Ferreira, R
Keywords: UE-ME3
antioxidant capacity
Issue Date: 2011
Publisher: Formatex
Citation: Candeias M, Alves-Pereira I, Ferreira R (2011) Differential response to isoproturon by two strains of Saccharomyces cerevisiae. IV International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2011), Torremolinos-Malaga (Spain)
Abstract: S. cerevisiae UE-ME3 grown in MB medium in the absence and presence of IPU show a similar growth profile and a stabilization of the biomass, non-protein thiols content, cell viability (cfu) and cell redox status estimated by GSH/GSSG ratio. This response seems depend on GR and G6PD activities increase, which probably activates the glutathione cycle, signs of adaptive response to phenylurea. However, S. cerevisiae IGC-4072 strain showed signs of cell death in the presence of IPU, exhibiting a more slowly growth profile, a decrease of dry weight and cell viability, as well as a significant increase of free radicals scavenger (DPPH) in presence of phenylurea, without significant changes of the GSH/GSSG ratio. As the value of the GSH/GSSG ratio is significant lower in IGC-4072 cells and GR activity undergoes a marked decrease in the presence of the IPU it is suspected that the worst IPU adaptive capacity displayed by this strain depends on a poor antioxidant power mediated by the glutathione.
Type: article
Appears in Collections:MED - Artigos em Livros de Actas/Proceedings
QUI - Artigos em Livros de Actas/Proceedings

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