Please use this identifier to cite or link to this item:

Title: Histopathological features of organs in a rat model of mammary carcinogenesis: a reference database
Authors: Helena, Vala
Vasconcelos-Nóbrega, Carmen
Gama, Adelina
Ferreira, Rita
Oliveira, Paula Alexandra
Faustino-Rocha, Ana Isabel
Keywords: histological
rat model
Issue Date: 2020
Publisher: REDVET - Revista Electrónica de Veterinaria
Citation: Vala H, Vasconcelos-Nóbrega C, Gama A, Ferreira R, Oliveira PA, Faustino-Rocha AI. 2020. Histopathological features of organs in a rat model of mammary carcinogenesis: a reference database. REDVET - Revista Electrónica de Veterinaria 21(4): 12-24.
Abstract: Mammary tumors’ development was induced through the intraperioneal administration of the carcinogen N-methyl-N-nitrosourea (MNU). Animals from group control were injected with the vehicle (saline solution). Animals were sacrificed at 25 weeks-old and the organs were histopathologically evaluated. A higher number of lesions was observed in the organs of animals from group MNU. The animals from group control did not present any lesion in lymph nodes. Independently of the experimental group, the internal organs presented hemodynamic alterations, degenerative and inflammatory changes. Hemodynamic changes may be consequence of euthanasia method. As expected, the higher number and the higher grade of the lesions in group MNU were due to the carcinogen administration.
ISSN: 1695-7504
Type: article
Appears in Collections:ZOO - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

Files in This Item:

File Description SizeFormat
Histopathological features.pdf562.25 kBAdobe PDFView/Open
FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpaceOrkut
Formato BibTex mendeley Endnote Logotipo do DeGóis 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Dspace Dspace
DSpace Software, version 1.6.2 Copyright © 2002-2008 MIT and Hewlett-Packard - Feedback
UEvora B-On Curriculum DeGois