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Title: Recent advances in the asymmetric catalytic synthesis of chiral 3-hydroxy and 3-aminooxindoles and derivatives: Medicinally relevant compounds
Authors: Burke, Anthony
Brandão, Pedro
Editors: Motherwell, Willian
Zard, Samir
Keywords: Catálise
Issue Date: 20-Sep-2018
Publisher: Elsevier
Abstract: Several oxindole derivatives, of natural or synthetic origin, have been identified as medicinally appealing compounds, with a plethora of bioactivities reported. Chiral 3-hydroxy and 3-aminooxindole scaffolds have captured the attention of several research groups, due to their importance in drug discovery. In this review, we systematically address the wide variety of asymmetric catalytic methodologies employed in the preparation of these relevant chiral scaffolds, present in many biologically active compounds and/or natural products. Special focus will be given to the nature of the catalyst used.
Type: book
Appears in Collections:CQE - Publicações - Livros

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