Please use this identifier to cite or link to this item: http://hdl.handle.net/10174/15762

Title: A Soft Computing Approach to Kidney Diseases Evaluation
Authors: Neves, José
Martins, M. Rosário
Vilhena, João
Neves, João
Gomes, Sabino
Abelha, António
Machado, José
Vicente, Henrique
Keywords: Kidney Disease
Soft Computing
Artificial Neural Networks
Incomplete Information
Logic Programming
Knowledge Representation and Reasoning
Issue Date: 2015
Publisher: Springer, New York
Citation: Neves, J., Martins, M.R., Vilhena, J., Neves, J., Gomes, S., Abelha, A., Machado, J. & Vicente, H., A Soft Computing Approach to Kidney Diseases Evaluation. Journal of Medical Systems, 39 (10): 131, 9 pages, 2015.
Abstract: Kidney renal failure means that one’s kidney have unexpectedly stopped functioning, i.e., once chronic disease is exposed, the presence or degree of kidney dysfunction and its progression must be assessed, and the underlying syndrome has to be diagnosed. Although the patient’s history and physical examination may denote good practice, some key information has to be obtained from valuation of the glomerular filtration rate, and the analysis of serum biomarkers. Indeed, chronic kidney sickness depicts anomalous kidney function and/or its makeup, i.e., there is evidence that treatment may avoid or delay its progression, either by reducing and prevent the development of some associated complications, namely hypertension, obesity, diabetes mellitus, and cardiovascular complications. Acute kidney injury appears abruptly, with a rapid deterioration of the renal function, but is often reversible if it is recognized early and treated promptly. In both situations, i.e., acute kidney injury and chronic kidney disease, an early intervention can significantly improve the prognosis. The assessment of these pathologies is therefore mandatory, although it is hard to do it with traditional methodologies and existing tools for problem solving. Hence, in this work, we will focus on the development of a hybrid decision support system, in terms of its knowledge representation and reasoning procedures based on Logic Programming, that will allow one to consider incomplete, unknown, and even contradictory information, complemented with an approach to computing centered on Artificial Neural Networks, in order to weigh the Degree-of-Confidence that one has on such a happening. The present study involved 558 patients with an age average of 51.7 years and the chronic kidney disease was observed in 175 cases. The dataset comprise twenty four variables, grouped into five main categories. The proposed model showed a good performance in the diagnosis of chronic kidney disease, since the sensitivity and the specificity exhibited values range between 93.1–94.9 % and 91.9–94.2 %, respectively.
URI: http://link.springer.com/article/10.1007/s10916-015-0313-4
http://hdl.handle.net/10174/15762
ISSN: 0148-5598 (Print)
1573-689X (Online)
Type: article
Appears in Collections:ICAAM - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
QUI - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica
CQE - Publicações - Artigos em Revistas Internacionais Com Arbitragem Científica

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