DSpace Collection:http://hdl.handle.net/10174/6642026-04-03T22:59:24Z2026-04-03T22:59:24ZChapter 16: Animal models in phytopharmacology and toxicological testing of plant productsFaustino-Rocha, AIMedeiros-Fonseca, BOliveira, PAhttp://hdl.handle.net/10174/391692025-08-27T23:06:28Z2023-01-01T00:00:00ZTitle: Chapter 16: Animal models in phytopharmacology and toxicological testing of plant products
Authors: Faustino-Rocha, AI; Medeiros-Fonseca, B; Oliveira, PA
Abstract: Chapter 16: Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants2023-01-01T00:00:00ZChapter: Carcinogenesis.Jota Baptista, CFaustino-Rocha, AISeixas, FOliveira, PAhttp://hdl.handle.net/10174/391662025-08-27T23:05:24Z2023-01-01T00:00:00ZTitle: Chapter: Carcinogenesis.
Authors: Jota Baptista, C; Faustino-Rocha, AI; Seixas, F; Oliveira, PA
Abstract: Cancer is a complex disease with multiple causes. Many intrinsic and extrinsic factors influence the development of cancer. Intrinsic or host factors include age, sex, genetics, immune system, metabolism, and hormones. Extrinsic factors are divided in different groups, as physical (different types of non-ionizing and ionizing radiations); chemical (as some mineral or organic substances); and biological (produced by some living organisms, for instance, some plants, virus, bacteria or fungi). Intrinsic and extrinsic factors can interact with one another to influence the development of cancer. In this article, we will discuss all the varied aspects of research that will ultimately lead to the prevention of cancer in man.2023-01-01T00:00:00ZChemical carcinogensOliveira, PAFaustino-Rocha, AIhttp://hdl.handle.net/10174/391562025-08-27T23:01:45Z2023-01-01T00:00:00ZTitle: Chemical carcinogens
Authors: Oliveira, PA; Faustino-Rocha, AI
Abstract: This chapter is part of the Handbook of Cancer and Immunology, composed of various volumes addressing several aspects of different cancers, like cancer biology, immunology, interaction with microenvironment, diagnosis, and treatment. This work aimed to provide the readers with an overview of chemical carcinogens, reviewing origin of these chemical agents, their classification, and metabolization, beyond the process of carcinogenesis and the role of these compounds on it. Chemical carcinogens may be classified as genotoxic or non-genotoxic considering its interaction or not with cells’ DNA. Approximately 25% of all chemical carcinogens are considered direct compounds, interacting with DNA without previous metabolization. Chemical carcinogens have been used for many years to induce cancer development in target organs in several experimental assays, and their effectiveness depends on the species, dose, route and duration of exposure, and the animals’ age at the administration. An illustration of the process of carcinogenesis and its interaction with the chemical compounds was provided, as well as a list of chemical compounds carcinogenic and probably carcinogenic to humans. This chapter was written by two researchers with a settled experience in the field of oncology, mainly on the development of animal models of cancer chemically induced.2023-01-01T00:00:00ZSEA LAMPREY (PETROMYZON MARINUS L.), A DELICACY WITH HIGH GASTRONOMIC IMPACT IN SEVERAL COUNTRIES OF WESTERN EUROPE: NUTRITIONAL COMPOSITION AND HEALTHY LIPID INDEX OF FILLETSVentura, HugoMachado, Maria da GraçaLança, Maria Joãohttp://hdl.handle.net/10174/368772024-05-27T14:01:00Z2024-04-07T23:00:00ZTitle: SEA LAMPREY (PETROMYZON MARINUS L.), A DELICACY WITH HIGH GASTRONOMIC IMPACT IN SEVERAL COUNTRIES OF WESTERN EUROPE: NUTRITIONAL COMPOSITION AND HEALTHY LIPID INDEX OF FILLETS
Authors: Ventura, Hugo; Machado, Maria da Graça; Lança, Maria João
Editors: Atena Editora
Abstract: RESUMO: Nalguns países, a lampreia-marinha (Petromyzon marinus L.) é considerada uma
iguaria e é capturada intensivamente durante a migração reprodutiva, sendo a sua pesca
uma importante fonte de rendimento para os pescadores comerciais de interior na Europa
Ocidental (Portugal, Espanha, França), fornecendo centenas de milhares de lampreias marinhas para restaurantes todos os anos. Em Portugal é vendida a preços elevados em
restaurantes onde são consumidas anualmente dezenas de milhares de lampreias-marinhas.
Este trabalho caracteriza a composição centesimal dos filetes de lampreia-marinha,
fornecendo o perfil de ácidos gordos, proteína bruta total, colesterol total, macro e micro minerais, teor de energia bruta e índices lipídicos saudáveis.2024-04-07T23:00:00Z